Pilot #6 (DEMΒ.C1): Early identification of dementia on patients with early signs of sarcopenia and frailty

Frailty and sarcopenia, often present years before Alzheimer’s disease (AD), manifest as poor physical health symptoms like balance issues, body weakness, and gait problems. The link between these early signs and dementia development is under-researched. This pilot aims to identify early risk factors to prevent cognitive decline and improve self-management and quality of life in older adults. The study will involve older adults diagnosed with frailty, sarcopenia, and healthy controls. Data collection will include physical measurements, neuropsychological evaluations, gait analysis, heart rate biomarkers, and lifestyle metrics like nutrition. The findings will help design a roadmap to prevent cognitive decline by identifying biomarkers and risk factors for early intervention and personalised healthcare plans.

Keys

Key outcomes include identifying the pre-dementia stage and preventive approaches, with KPIs of identifying over eight dementia risk factors and improving quality of life by over 30%.
Cluster
Cluster #B - Study of the Association Between the Development of Dementia and Other Health Conditions
Manager
Aristotle University of Thessaloniki
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